Tumor-Induced Osteomalacia: A Case Report of Rare Disease and Literature review

نویسندگان

چکیده

Background Oncogenic osteomalacia term used for tumor-induced (TIO) is a paraneoplastic syndrome of abnormal phosphate metabolism secondary to ectopic endocrine tumors. The diagnosis often becomes difficult due rarity occurrence and deficient literature. reconstruction following resection has its own technical difficulties, which are addressed in this article. Presentation Case A 39-year-old female presented with pain bilateral lower limbs difficulty mobilizing. patient had unexplained hypophosphatemia was diagnosed tumor (arising ectopically greater trochanter), inducing osteomalacia. She managed successfully excision reconstruction. biochemical parameters improved drastically within 5 days fracture healed 6 weeks' time. Conclusion TIO debilitating disease significant morbidity prolonged onset interval localizing the causative tumor. So thorough clinico-radiological laboratory parameter correlation necessity. rapid followed by complete surgical excision, remains gold standard treatment modality that confers favorable prognosis most patients, strict vigilance recurrence required.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

TUMOR ASSOCIATED OSTEOMALACIA IN NEUROFIBROMATOSIS: CASE REPORT AND LITERATURE REVIEW

The association of osteomalacia with neurofibromatosis is a very rare entity. Here a 34 year old man, a known case of neurofibromatosis, is reported who presented with bone pain, hypophosphatemia, rena] phosphorus wasting, multiple Looser's pseudofractures, and low bone density. Treatment with high dose calcitriol and phosphate resulted in temporary treatment. Permanent cure was achieved a...

متن کامل

Tumour-induced osteomalacia: a literature review and a case report.

Tumour-induced osteomalacia (TIO) is a rare paraneoplastic syndrome characterised by severe hypophosphataemia and osteomalacia, with renal phosphate wasting that occurs in association with tumour. The epidemiology likewise aetiology is not known. The clinical presentation of TIO includes bone fractures, bone and muscular pains, and sometimes height and weight loss. TIO may be associated with me...

متن کامل

tumor associated osteomalacia in neurofibromatosis: case report and literature review

the association of osteomalacia with neurofibromatosis is a very rare entity. here a 34 year old man, a known case of neurofibromatosis, is reported who presented with bone pain, hypophosphatemia, rena] phosphorus wasting, multiple looser's pseudofractures, and low bone density. treatment with high dose calcitriol and phosphate resulted in temporary treatment. permanent cure was achieved a...

متن کامل

The Foot That Broke Both Hips: A Case Report and Literature Review of Tumor-Induced Osteomalacia

Tumor-induced osteomalacia (TIO) is a rare paraneoplastic syndrome characterized by hypophosphatemia and clinical symptoms of osteomalacia. Only discussed as case reports, there is still limited knowledge of this condition as a potentially curable cause of osteomalacia among clinicians and pathologists. In this article, we present a case of tumor-induced osteomalacia in a 59-year-old gentleman ...

متن کامل

Tumor induced osteomalacia secondary to anaplastic thyroid carcinoma: A case report and review of the literature

CONTEXT Tumor induced osteomalacia related to anaplastic thyroid cancer has never been reported. OBJECTIVE We describe a case of tumor induced osteomalacia (TIO) in a patient with a fibroblast growth factor 23 (FGF-23) secreting anaplastic thyroid carcinoma. The current imaging modalities are reviewed. DESIGN AND INTERVENTION Clinical, biochemical, and radiological assessments were done, in...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: South Asian Journal of Cancer

سال: 2023

ISSN: ['2278-330X', '2278-4306']

DOI: https://doi.org/10.1055/s-0043-1768681